Chemotaxis in cancer
نویسندگان
چکیده
منابع مشابه
Induced Chemotaxis of Human Breast Cancer Cells
Chemotaxis plays an important role in cancer cell metastasis. In this study, we showed that epidermal growth factor (EGF) was a more potent chemoattractant than chemokine SDF-1a/ CXCL12 for human breast cancer cell MDA-MB-231. Different inhibitors were used to evaluate the involvement of 12 protein kinase C (PKC) isotypes in the chemotactic signaling pathway. Chelerythrine chloride, an inhibito...
متن کاملRole for ezrin in breast cancer cell chemotaxis to CCL5.
This study was undertaken to observe the effects and the possible mechanism of membrane-cytoskeleton linker ezrin on the chemokine CC chemokine ligand 5 (CCL5)-induced invasive ability in human breast carcinoma MCF-7 cells. RNA interference (RNAi) using ezrin small hairpin RNAs (ezrin shRNA) was used to analyze the role of ezrin in the regulation of this CCL5-induced malignant behavior of MCF-7...
متن کاملChemotaxis in Methanospirillum hungatei.
Methanospirillum hungatei gave a positive chemotactic response to acetate.
متن کاملChemotaxis in bacteria.
Bacterial chemotaxis, the movement of motile bacteria toward or away from chemicals, was discovered nearly a century ago by Engelmann (1) and Pfeffer (2,3). The subject was actively studied for about 50 years, but then there were very few reports until quite recently. For reviews of the literature up to about 1960, see Berg (4), Weibull (5), and Ziegler (6). The present review will restrict its...
متن کاملChemotaxis in Vibrio cholerae.
The ability of motile bacteria to swim toward or away from specific environmental stimuli, such as nutrients, oxygen, or light provides cells with a survival advantage, especially under nutrient-limiting conditions. This behavior, called chemotaxis, is mediated by the bacteria changing direction by briefly reversing the direction of rotation of the flagellar motors. A sophisticated signal trans...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2011
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc3078